Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808