Disease: Scleroderma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC6 O95255 ATP binding cassette subfamily C member 6 Transporter 5.6E-35 0.540 0.654
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CSF1 P09603 colony stimulating factor 1 1.00 0.473 0.808
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERAL1 O75616 Era like 12S mitochondrial rRNA chaperone 1 Enzyme modulator 3.1E-09 0.638 0.577
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FGF23 Q9GZV9 fibroblast growth factor 23 Signaling 3.1E-02 0.460 0.731
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
LOX P28300 lysyl oxidase 0.99 0.447 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923