Disease: Idiopathic pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
ANO1 Q5XXA6 anoctamin 1 Ion channel 0.87 0.516 0.769
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CFH P08603 complement factor H 0.86 0.441 0.885
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
DNER Q8NFT8 delta/notch like EGF repeat containing 0.19 0.493 0.769
DUOX1 Q9NRD9 dual oxidase 1 Enzyme 6.2E-33 0.570 0.692
DUOX2 Q9NRD8 dual oxidase 2 Enzyme 4.5E-56 0.533 0.769