Disease: Sudden Cardiac Death
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SCN10A Q9Y5Y9 sodium voltage-gated channel alpha subunit 10 Ion channel 9.9E-38 0.566 0.692
TRPM4 Q8TD43 transient receptor potential cation channel subfamily M member 4 Ion channel 5.7E-33 0.633 0.577
TRDN Q13061 triadin 8.4E-22 0.691 0.462
PKP2 Q99959 plakophilin 2 Cellular structure 3.1E-18 0.606 0.538
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
TMEM43 Q9BTV4 transmembrane protein 43 1.2E-12 0.653 0.462
CASQ2 O14958 calsequestrin 2 1.4E-12 0.691 0.385
MYBPC3 Q14896 myosin binding protein C3 8.0E-11 0.593 0.385
DSG2 Q14126 desmoglein 2 Cell adhesion 2.8E-10 0.601 0.692
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
DSC2 Q02487 desmocollin 2 Cell adhesion 5.2E-08 0.610 0.538
KCNE2 Q9Y6J6 potassium voltage-gated channel subfamily E regulatory subunit 2 Ion channel 1.0E-04 0.628 0.423
JUP P14923 junction plakoglobin 8.0E-04 0.628 0.500
TNNT2 P45379 troponin T2, cardiac type Cellular structure 2.0E-03 0.601 0.423
KCNE1 P15382 potassium voltage-gated channel subfamily E regulatory subunit 1 Ion channel 3.4E-03 0.588 0.615
CAV3 P56539 caveolin 3 Enzyme modulator 5.5E-03 0.564 0.692
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
TNNI3 P19429 troponin I3, cardiac type Cellular structure 9.6E-02 0.520 0.769
KCNJ2 P63252 potassium inwardly rectifying channel subfamily J member 2 Ion channel 0.31 0.572 0.731
PLN P26678 phospholamban 0.45 0.595 0.577
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
NOS1AP O75052 nitric oxide synthase 1 adaptor protein Signaling 0.61 0.608 0.423
DTNA Q9Y4J8 dystrobrevin alpha 0.63 0.695 0.385
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692