Disease: Heart Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TNNT2 P45379 troponin T2, cardiac type Cellular structure 2.0E-03 0.601 0.423
TNNI3 P19429 troponin I3, cardiac type Cellular structure 9.6E-02 0.520 0.769
TPM1 P09493 tropomyosin 1 Cellular structure 1.0E-03 0.560 0.615
TRPM4 Q8TD43 transient receptor potential cation channel subfamily M member 4 Ion channel 5.7E-33 0.633 0.577
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654
SCN10A Q9Y5Y9 sodium voltage-gated channel alpha subunit 10 Ion channel 9.9E-38 0.566 0.692
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615
RBM20 Q5T481 RNA binding motif protein 20 0.99 0.716 0.269
RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 Enzyme modulator 7.1E-23 0.593 0.692
COPD Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
KCNH2 Q12809 potassium voltage-gated channel subfamily H member 2 Ion channel 1.00 0.522 0.731
KCNE1 P15382 potassium voltage-gated channel subfamily E regulatory subunit 1 Ion channel 3.4E-03 0.588 0.615
KCNIP2 Q9NS61 potassium voltage-gated channel interacting protein 2 Ion channel 1.5E-02 0.821 0.077
KCNJ2 P63252 potassium inwardly rectifying channel subfamily J member 2 Ion channel 0.31 0.572 0.731
PKP2 Q99959 plakophilin 2 Cellular structure 3.1E-18 0.606 0.538
PLN P26678 phospholamban 0.45 0.595 0.577
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731