Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
TRPV4 | Q9HBA0 | transient receptor potential cation channel subfamily V member 4 | Ion channel | 2.2E-16 | 0.457 | 0.808 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
TH | P07101 | tyrosine hydroxylase | 1.7E-06 | 0.462 | 0.885 | |
RYR1 | P21817 | ryanodine receptor 1 | Ion channel | 1.6E-29 | 0.489 | 0.808 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
ERBB3 | P21860 | erb-b2 receptor tyrosine kinase 3 | Kinase | 1.7E-15 | 0.448 | 0.808 |
TPO | P07202 | thyroid peroxidase | Enzyme | 1.8E-21 | 0.455 | 0.846 |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
PINK1 | Q9BXM7 | PTEN induced kinase 1 | Kinase | 1.9E-10 | 0.516 | 0.769 |
DNM2 | P50570 | dynamin 2 | Enzyme modulator | 1.00 | 0.542 | 0.769 |
PANK2 | Q9BZ23 | pantothenate kinase 2 | Kinase | 7.4E-07 | 0.559 | 0.808 |
EEF1A2 | Q05639 | eukaryotic translation elongation factor 1 alpha 2 | Enzyme | 1.00 | 0.554 | 0.808 |
ATP13A2 | Q9NQ11 | ATPase cation transporting 13A2 | 9.0E-09 | 0.566 | 0.577 | |
PODXL | O00592 | podocalyxin like | 1.0E-03 | 0.551 | 0.731 | |
ZC4H2 | Q9NQZ6 | zinc finger C4H2-type containing | 0.91 | 0.561 | 0.731 | |
MUSK | O15146 | muscle associated receptor tyrosine kinase | Kinase | 4.2E-08 | 0.570 | 0.769 |
SPG11 | Q96JI7 | SPG11 vesicle trafficking associated, spatacsin | 1.6E-39 | 0.576 | 0.538 | |
EIF4G1 | Q04637 | eukaryotic translation initiation factor 4 gamma 1 | Nucleic acid binding | 1.00 | 0.553 | 0.808 |
SYNJ1 | O43426 | synaptojanin 1 | Enzyme | 0.43 | 0.576 | 0.577 |
CHRNG | P07510 | cholinergic receptor nicotinic gamma subunit | Ion channel | 3.3E-19 | 0.573 | 0.692 |