Disease: Myelodysplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
DDX41 Q9UJV9 DEAD-box helicase 41 5.6E-08 0.636 0.538
ELANE P08246 elastase, neutrophil expressed Enzyme 1.2E-03 0.447 0.846
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
GFI1 Q99684 growth factor independent 1 transcriptional repressor Transcription factor 0.25 0.546 0.769
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IL6 P05231 interleukin 6 0.32 0.248 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SRP54 P61011 signal recognition particle 54 Nucleic acid binding 1.00 0.612 0.769
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
TCIRG1 Q13488 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 Transporter 2.4E-13 0.565 0.692
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962