Disease: Alcohol Use Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TAS2R16 Q9NYV7 taste 2 receptor member 16 G-protein coupled receptor 0.736 0.192
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
ADH4 P08319 alcohol dehydrogenase 4 (class II), pi polypeptide Enzyme 8.1E-07 0.641 0.462
LHB P01229 luteinizing hormone subunit beta Signaling 2.2E-03 0.638 0.462
OPRL1 P41146 opioid related nociceptin receptor 1 G-protein coupled receptor 0.48 0.628 0.462
TBX19 O60806 T-box transcription factor 19 Transcription factor 7.1E-06 0.695 0.462
CDK20 Q8IZL9 cyclin dependent kinase 20 Kinase 5.9E-14 0.682 0.462
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
CCKAR P32238 cholecystokinin A receptor G-protein coupled receptor 4.0E-03 0.615 0.500
GPHN Q9NQX3 gephyrin 1.00 0.608 0.538
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FSHB P01225 follicle stimulating hormone subunit beta Signaling 0.34 0.631 0.577
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577
NPY2R P49146 neuropeptide Y receptor Y2 G-protein coupled receptor 3.6E-02 0.612 0.577
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
MCM5 P33992 minichromosome maintenance complex component 5 Nucleic acid binding 5.9E-04 0.617 0.615
GABRG2 P18507 gamma-aminobutyric acid type A receptor subunit gamma2 Ion channel 0.74 0.548 0.654
ARNTL2 Q8WYA1 aryl hydrocarbon receptor nuclear translocator like 2 Transcription factor 6.0E-10 0.644 0.654
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
ADH1C P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 0.547 0.731
PDE4B Q07343 phosphodiesterase 4B 0.47 0.566 0.731
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769