Disease: CNS disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FZD4 Q9ULV1 frizzled class receptor 4 G-protein coupled receptor 0.97 0.490 0.923
GPR151 Q8TDV0 G protein-coupled receptor 151 G-protein coupled receptor 3.2E-08 0.530 0.923
GPR166P G protein-coupled receptor 166 pseudogene 0.531 0.923
GPRC6A Q5T6X5 G protein-coupled receptor class C group 6 member A G-protein coupled receptor 5.6E-17 0.526 0.923
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
LGR6 Q9HBX8 leucine rich repeat containing G protein-coupled receptor 6 G-protein coupled receptor 2.9E-06 0.502 0.923
LPAR3 Q9UBY5 lysophosphatidic acid receptor 3 G-protein coupled receptor 0.68 0.509 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MRGPRX1 Q96LB2 MAS related GPR family member X1 G-protein coupled receptor 0.531 0.923
MRGPRX3 Q96LB0 MAS related GPR family member X3 G-protein coupled receptor 0.529 0.923
MRGPRX4 Q96LA9 MAS related GPR family member X4 G-protein coupled receptor 0.531 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885