Disease: Nicotine Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
ADH1C P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 0.547 0.731
AKR1A1 P14550 aldo-keto reductase family 1 member A1 Enzyme 6.7E-07 0.510 0.846
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885
CYP3A5 P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 6.3E-17 0.511 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
GABBR1 Q9UBS5 gamma-aminobutyric acid type B receptor subunit 1 G-protein coupled receptor 1.00 0.587 0.769
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846