Disease: Mixed anxiety and depressive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FZD4 Q9ULV1 frizzled class receptor 4 G-protein coupled receptor 0.97 0.490 0.923
GPR151 Q8TDV0 G protein-coupled receptor 151 G-protein coupled receptor 3.2E-08 0.530 0.923
GPR166P G protein-coupled receptor 166 pseudogene 0.531 0.923
GPRC6A Q5T6X5 G protein-coupled receptor class C group 6 member A G-protein coupled receptor 5.6E-17 0.526 0.923
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
LEP P41159 leptin 0.46 0.349 0.846
LGR6 Q9HBX8 leucine rich repeat containing G protein-coupled receptor 6 G-protein coupled receptor 2.9E-06 0.502 0.923
LPAR3 Q9UBY5 lysophosphatidic acid receptor 3 G-protein coupled receptor 0.68 0.509 0.923
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MRGPRX1 Q96LB2 MAS related GPR family member X1 G-protein coupled receptor 0.531 0.923
MRGPRX3 Q96LB0 MAS related GPR family member X3 G-protein coupled receptor 0.529 0.923