Disease: Drug Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
ADH4 P08319 alcohol dehydrogenase 4 (class II), pi polypeptide Enzyme 8.1E-07 0.641 0.462
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846
GHSR Q92847 growth hormone secretagogue receptor G-protein coupled receptor 6.6E-03 0.528 0.769
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MARCHF11 A6NNE9 membrane associated ring-CH-type finger 11 3.1E-03 0.769 0.385