Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
FLNA P21333 filamin A 1.00 0.419 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ATN1 P54259 atrophin 1 1.00 0.409 0.885
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
FLNB O75369 filamin B 6.1E-10 0.458 0.923
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769