Disease: Common Variable Immunodeficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APCS P02743 amyloid P component, serum 3.2E-02 0.531 0.808
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808
CD19 P15391 CD19 molecule 0.90 0.430 0.885
CD27 P26842 CD27 molecule 1.0E-02 0.517 0.692
CD40 P25942 CD40 molecule 0.85 0.396 0.846
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846
CD70 P32970 CD70 molecule 1.0E-02 0.542 0.692
CD81 P60033 CD81 molecule 0.92 0.555 0.846
CR2 P20023 complement C3d receptor 2 4.7E-19 0.556 0.654
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731
ICOSLG O75144 inducible T cell costimulator ligand 3.5E-04 0.601 0.654
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
ITK Q08881 IL2 inducible T cell kinase Kinase 3.1E-08 0.555 0.769
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
LRBA P50851 LPS responsive beige-like anchor protein 7.2E-12 0.608 0.692
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
NFKB2 Q00653 nuclear factor kappa B subunit 2 Transcription factor 1.00 0.509 0.808
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
RAG2 P55895 recombination activating 2 2.0E-02 0.507 0.769