Disease: Aortic Valve Insufficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CCNQ Q8N1B3 cyclin Q Enzyme modulator 0.90 0.663 0.462
MFAP5 Q13361 microfibril associated protein 5 5.1E-03 0.590 0.615
GATA5 Q9BWX5 GATA binding protein 5 0.28 0.578 0.615
FOXE3 Q13461 forkhead box E3 Transcription factor 0.18 0.568 0.654
MAT2A P31153 methionine adenosyltransferase 2A Enzyme 1.00 0.615 0.654
SKIV2L Q15477 Ski2 like RNA helicase 1.3E-22 0.615 0.654
TTC37 Q6PGP7 tetratricopeptide repeat domain 37 1.7E-29 0.626 0.654
TAB2 Q9NYJ8 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 1.00 0.617 0.654
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692
SMAD6 O43541 SMAD family member 6 Transcription factor 3.6E-20 0.579 0.731
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
QRSL1 Q9H0R6 glutaminyl-tRNA amidotransferase subunit QRSL1 Enzyme 4.9E-08 0.563 0.731
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
JUNB P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.86 0.467 0.769
PRKG1 Q13976 protein kinase cGMP-dependent 1 Kinase 1.00 0.603 0.769
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769
JUND P17535 JunD proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.70 0.475 0.808
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FLNA P21333 filamin A 1.00 0.419 0.846
FOSB P53539 FosB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.98 0.463 0.846
LOX P28300 lysyl oxidase 0.99 0.447 0.846