Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
ADRA2B P18089 adrenoceptor alpha 2B G-protein coupled receptor 4.5E-06 0.465 0.846
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
IL12B P29460 interleukin 12B Signaling 1.1E-04 0.480 0.885
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769