Disease: Migraine with Aura
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RLS1 Restless legs syndrome, susceptibility to 0.705 0.423
MGR6 Migraine, several forms 0.890 0.154
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
TRPA1 O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 7.2E-35 0.546 0.846
TRPM8 Q7Z2W7 transient receptor potential cation channel subfamily M member 8 Ion channel 4.6E-29 0.553 0.808
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
TRPV3 Q8NET8 transient receptor potential cation channel subfamily V member 3 Ion channel 4.6E-20 0.610 0.577
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808
CSAD Q9Y600 cysteine sulfinic acid decarboxylase Enzyme 6.1E-12 0.678 0.538
FSHR P23945 follicle stimulating hormone receptor G-protein coupled receptor 1.4E-11 0.539 0.654
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
PRDX1 Q06830 peroxiredoxin 1 Enzyme 7.7E-10 0.485 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TGFBI Q15582 transforming growth factor beta induced Signaling 6.0E-08 0.484 0.769
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885