Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
SMARCA2 P51531 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Epigenetic regulator 1.00 0.527 0.769
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808
CTSS P25774 cathepsin S Enzyme 0.34 0.539 0.731
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692