Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
IGAN1 IgA nephropathy 0.524 0.808
MIR15B microRNA 15b 0.532 0.769
RAB7B Q96AH8 RAB7B, member RAS oncogene family 0.615 0.731
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
VPS13A Q96RL7 vacuolar protein sorting 13 homolog A 9.3E-22 0.650 0.577
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731
TDP1 Q9NUW8 tyrosyl-DNA phosphodiesterase 1 Enzyme 1.3E-17 0.612 0.538
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
IGHMBP2 P38935 immunoglobulin mu DNA binding protein 2 3.0E-16 0.636 0.615
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769
AAAS Q9NRG9 aladin WD repeat nucleoporin 2.4E-13 0.601 0.654
SAMHD1 Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 6.5E-13 0.547 0.769
P2RX4 Q99571 purinergic receptor P2X 4 Ion channel 5.0E-12 0.547 0.808
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
CRAT P43155 carnitine O-acetyltransferase Enzyme 9.5E-12 0.656 0.577
SPTLC1 O15269 serine palmitoyltransferase long chain base subunit 1 Enzyme 4.2E-11 0.650 0.538
TOP3A Q13472 DNA topoisomerase III alpha Enzyme 5.1E-11 0.656 0.615
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923