KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
GNAS |
O95467 P63092 P84996 Q5JWF2
|
GNAS complex locus
|
Enzyme modulator
|
0.68 |
0.420 |
0.885 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
ERCC3 |
P19447
|
ERCC excision repair 3, TFIIH core complex helicase subunit
|
Enzyme
|
3.4E-11 |
0.504 |
0.846 |
CREBBP |
Q92793
|
CREB binding protein
|
|
1.00 |
0.428 |
0.808 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
RAF1 |
P04049
|
Raf-1 proto-oncogene, serine/threonine kinase
|
Kinase
|
0.85 |
0.418 |
0.885 |
PLA2G6 |
O60733
|
phospholipase A2 group VI
|
Enzyme modulator
|
2.5E-10 |
0.476 |
0.846 |
MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
FANCA |
O15360
|
FA complementation group A
|
|
1.6E-68 |
0.505 |
0.731 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
MAP2K2 |
P36507
|
mitogen-activated protein kinase kinase 2
|
Kinase
|
0.97 |
0.534 |
0.731 |
MITF |
O75030
|
melanocyte inducing transcription factor
|
|
0.98 |
0.499 |
0.808 |
FTO |
Q9C0B1
|
FTO alpha-ketoglutarate dependent dioxygenase
|
|
8.4E-08 |
0.486 |
0.885 |
CYP21A2 |
P08686
|
cytochrome P450 family 21 subfamily A member 2
|
|
2.6E-04 |
0.525 |
0.769 |
KIT |
P10721
|
KIT proto-oncogene, receptor tyrosine kinase
|
Kinase
|
0.98 |
0.366 |
0.808 |
WDPCP |
O95876
|
WD repeat containing planar cell polarity effector
|
|
1.1E-10 |
0.576 |
0.769 |
EZH2 |
Q15910
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
Epigenetic regulator
|
1.00 |
0.376 |
0.885 |