Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
ERCC2 | P18074 | ERCC excision repair 2, TFIIH core complex helicase subunit | Enzyme | 7.1E-20 | 0.420 | 0.846 |
ATN1 | P54259 | atrophin 1 | 1.00 | 0.409 | 0.885 | |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
MME | P08473 | membrane metalloendopeptidase | Enzyme | 1.5E-18 | 0.407 | 0.808 |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
TTR | P02766 | transthyretin | Transporter | 0.52 | 0.423 | 0.885 |
WNK1 | Q9H4A3 | WNK lysine deficient protein kinase 1 | Kinase | 1.00 | 0.416 | 0.846 |
TRPV4 | Q9HBA0 | transient receptor potential cation channel subfamily V member 4 | Ion channel | 2.2E-16 | 0.457 | 0.808 |
HSPG2 | P98160 | heparan sulfate proteoglycan 2 | Enzyme modulator | 1.0E-19 | 0.438 | 0.885 |
HSPB1 | P04792 | heat shock protein family B (small) member 1 | 2.8E-07 | 0.436 | 0.808 | |
ARSA | P15289 | arylsulfatase A | Enzyme | 1.1E-11 | 0.448 | 0.923 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
WWOX | Q9NZC7 | WW domain containing oxidoreductase | Enzyme | 1.2E-15 | 0.453 | 0.808 |
ATP7A | Q04656 | ATPase copper transporting alpha | Transporter | 1.00 | 0.494 | 0.769 |
FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
PMP22 | Q01453 | peripheral myelin protein 22 | Cellular structure | 0.91 | 0.471 | 0.885 |
MFN2 | O95140 | mitofusin 2 | Enzyme | 0.99 | 0.471 | 0.846 |