Disease: Hyperkeratosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808
SULT2B1 O00204 sulfotransferase family 2B member 1 0.44 0.641 0.538
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
MPDU1 O75352 mannose-P-dolichol utilization defect 1 1.0E-05 0.682 0.500
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
STS P08842 steroid sulfatase Enzyme 0.81 0.431 0.846
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
NAGA P17050 alpha-N-acetylgalactosaminidase 1.8E-11 0.647 0.538
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TGM1 P22735 transglutaminase 1 Enzyme 2.3E-13 0.565 0.769
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
ALDH3A2 P51648 aldehyde dehydrogenase 3 family member A2 9.4E-06 0.619 0.769
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808