Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
HLA-B | P01889 | major histocompatibility complex, class I, B | 3.9E-05 | 0.379 | 0.885 | |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
CALR | P27797 | calreticulin | Calcium-binding protein | 0.89 | 0.413 | 0.923 |
MEFV | O15553 | MEFV innate immuity regulator, pyrin | 1.0E-14 | 0.440 | 0.885 | |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
TET2 | Q6N021 | tet methylcytosine dioxygenase 2 | 4.3E-54 | 0.458 | 0.808 | |
STAT4 | Q14765 | signal transducer and activator of transcription 4 | Nucleic acid binding | 0.77 | 0.471 | 0.769 |
IL23R | Q5VWK5 | interleukin 23 receptor | Signaling | 5.6E-04 | 0.466 | 0.769 |
CBS | P0DN79 P35520 | cystathionine beta-synthase | Enzyme | 3.1E-05 | 0.465 | 0.885 |
PROS1 | P07225 | protein S | 4.7E-04 | 0.467 | 0.846 | |
IL12A | P29459 | interleukin 12A | 4.7E-02 | 0.491 | 0.808 | |
MYH7 | P12883 | myosin heavy chain 7 | 4.2E-16 | 0.516 | 0.692 | |
MPL | P40238 | MPL proto-oncogene, thrombopoietin receptor | Receptor | 4.1E-09 | 0.510 | 0.692 |
SH2B3 | Q9UQQ2 | SH2B adaptor protein 3 | 1.0E-04 | 0.527 | 0.692 | |
CCR1 | P32246 | C-C motif chemokine receptor 1 | G-protein coupled receptor | 0.39 | 0.531 | 0.769 |
THPO | P40225 | thrombopoietin | 0.20 | 0.513 | 0.692 | |
SERPINC1 | P01008 | serpin family C member 1 | Enzyme modulator | 1.00 | 0.507 | 0.769 |