Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
BPTF Q12830 bromodomain PHD finger transcription factor 1.00 0.560 0.769
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
KCNH1 O95259 potassium voltage-gated channel subfamily H member 1 Ion channel 0.55 0.542 0.731
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
TERC telomerase RNA component 0.471 0.846