Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846
MIR200C microRNA 200c 0.486 0.846
PAK1 Q13153 p21 (RAC1) activated kinase 1 Kinase 1.3E-03 0.494 0.808
SIX1 Q15475 SIX homeobox 1 Transcription factor 0.65 0.496 0.692
KDM6A O15550 lysine demethylase 6A Epigenetic regulator 1.00 0.498 0.769
HSPA9 P38646 heat shock protein family A (Hsp70) member 9 0.97 0.502 0.885
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
FGF3 P11487 fibroblast growth factor 3 Signaling 9.3E-05 0.505 0.808
MIR451A microRNA 451a 0.505 0.769
NSD2 O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 1.00 0.507 0.769
OTX2 P32243 orthodenticle homeobox 2 Transcription factor 0.92 0.514 0.808
SEMA3E O15041 semaphorin 3E Signaling 8.7E-09 0.515 0.769