Disease: Neural Tube Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SEC24B O95487 SEC24 homolog B, COPII coat complex component Transporter 1.00 0.890 0.192
CECR2 Q9BXF3 CECR2 histone acetyl-lysine reader Epigenetic regulator 1.00 0.743 0.385
ZIC5 Q96T25 Zic family member 5 Transcription factor 0.77 0.711 0.231
CELSR1 Q9NYQ6 cadherin EGF LAG seven-pass G-type receptor 1 G-protein coupled receptor 1.00 0.700 0.500
SCRIB Q14160 scribble planar cell polarity protein 0.93 0.691 0.423
TBXT O15178 T-box transcription factor T Transcription factor 2.4E-02 0.674 0.462
PRSS8 Q16651 serine protease 8 Enzyme 0.10 0.641 0.500
PRCP P42785 prolylcarboxypeptidase Enzyme 8.8E-12 0.633 0.692
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423
DVL2 O14641 dishevelled segment polarity protein 2 Signaling 1.4E-05 0.621 0.577
FUZ Q9BT04 fuzzy planar cell polarity protein 1.3E-05 0.597 0.731
BHMT Q93088 betaine--homocysteine S-methyltransferase 3.7E-14 0.595 0.731
PYY P10082 peptide YY Signaling 1.2E-02 0.588 0.615
VANGL2 Q9ULK5 VANGL planar cell polarity protein 2 0.84 0.588 0.615
PGPEP1 Q9NXJ5 pyroglutamyl-peptidase I Enzyme 8.5E-03 0.581 0.769
GRHL3 Q8TE85 grainyhead like transcription factor 3 Transcription factor 0.99 0.572 0.692
VANGL1 Q8TAA9 VANGL planar cell polarity protein 1 2.0E-02 0.570 0.538
PTK7 Q13308 protein tyrosine kinase 7 (inactive) Kinase 1.00 0.568 0.615
FOLR2 P14207 folate receptor beta 5.5E-06 0.559 0.654
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769
SPINT2 O43291 serine peptidase inhibitor, Kunitz type 2 7.5E-04 0.556 0.808
BMP1 P13497 bone morphogenetic protein 1 8.9E-04 0.554 0.769
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769
RRM1 P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 1.00 0.552 0.692
DACT1 Q9NYF0 dishevelled binding antagonist of beta catenin 1 0.40 0.547 0.692