Disease: Neural Tube Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SEC24B O95487 SEC24 homolog B, COPII coat complex component Transporter 1.00 0.890 0.192
TBXT O15178 T-box transcription factor T Transcription factor 2.4E-02 0.674 0.462
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769
GRHL3 Q8TE85 grainyhead like transcription factor 3 Transcription factor 0.99 0.572 0.692
ZIC5 Q96T25 Zic family member 5 Transcription factor 0.77 0.711 0.231
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
DVL2 O14641 dishevelled segment polarity protein 2 Signaling 1.4E-05 0.621 0.577
PYY P10082 peptide YY Signaling 1.2E-02 0.588 0.615
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
PTK7 Q13308 protein tyrosine kinase 7 (inactive) Kinase 1.00 0.568 0.615
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423
CELSR1 Q9NYQ6 cadherin EGF LAG seven-pass G-type receptor 1 G-protein coupled receptor 1.00 0.700 0.500
CECR2 Q9BXF3 CECR2 histone acetyl-lysine reader Epigenetic regulator 1.00 0.743 0.385
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769
PRCP P42785 prolylcarboxypeptidase Enzyme 8.8E-12 0.633 0.692
PRSS8 Q16651 serine protease 8 Enzyme 0.10 0.641 0.500
RRM1 P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 1.00 0.552 0.692
PGPEP1 Q9NXJ5 pyroglutamyl-peptidase I Enzyme 8.5E-03 0.581 0.769
BHMT Q93088 betaine--homocysteine S-methyltransferase 3.7E-14 0.595 0.731
BMP1 P13497 bone morphogenetic protein 1 8.9E-04 0.554 0.769
FOLR1 P15328 folate receptor alpha 0.13 0.522 0.885
FOLR2 P14207 folate receptor beta 5.5E-06 0.559 0.654