Disease: Neural Tube Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
DVL2 O14641 dishevelled segment polarity protein 2 Signaling 1.4E-05 0.621 0.577
TBXT O15178 T-box transcription factor T Transcription factor 2.4E-02 0.674 0.462
SPINT2 O43291 serine peptidase inhibitor, Kunitz type 2 7.5E-04 0.556 0.808
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769
SEC24B O95487 SEC24 homolog B, COPII coat complex component Transporter 1.00 0.890 0.192
INS P01308 insulin 0.30 0.445 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
PYY P10082 peptide YY Signaling 1.2E-02 0.588 0.615
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
BMP1 P13497 bone morphogenetic protein 1 8.9E-04 0.554 0.769
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
FOLR2 P14207 folate receptor beta 5.5E-06 0.559 0.654
FOLR1 P15328 folate receptor alpha 0.13 0.522 0.885
PAX3 P23760 paired box 3 0.24 0.481 0.769
RRM1 P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 1.00 0.552 0.692
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423
PRCP P42785 prolylcarboxypeptidase Enzyme 8.8E-12 0.633 0.692
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
PTK7 Q13308 protein tyrosine kinase 7 (inactive) Kinase 1.00 0.568 0.615