Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
FLNB O75369 filamin B 6.1E-10 0.458 0.923