Disease: Senile Plaques
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CLU P10909 clusterin 7.8E-05 0.426 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MIR342 microRNA 342 0.547 0.769
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923