Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GLS O94925 glutaminase Enzyme 0.96 0.489 0.808
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MFGE8 Q08431 milk fat globule-EGF factor 8 protein Enzyme 4.4E-05 0.548 0.808
NEFL P07196 neurofilament light 0.488 0.769
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PDK1 Q15118 pyruvate dehydrogenase kinase 1 Kinase 1.1E-05 0.510 0.808
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
SLC1A3 P43003 solute carrier family 1 member 3 Transporter 0.99 0.573 0.577
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SNCB Q16143 synuclein beta Transporter 6.8E-02 0.619 0.577
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923