Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
CASP1 | P29466 | caspase 1 | Enzyme | 3.5E-05 | 0.413 | 0.885 |
CHRM1 | P11229 | cholinergic receptor muscarinic 1 | G-protein coupled receptor | 0.99 | 0.653 | 0.577 |
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
CX3CR1 | P49238 | C-X3-C motif chemokine receptor 1 | G-protein coupled receptor | 6.1E-02 | 0.457 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
NFE2L2 | Q16236 | nuclear factor, erythroid 2 like 2 | Enzyme | 3.6E-03 | 0.357 | 0.885 |
NGF | P01138 | nerve growth factor | Signaling | 0.82 | 0.391 | 0.885 |
NLRP3 | Q96P20 | NLR family pyrin domain containing 3 | 8.1E-04 | 0.361 | 0.962 | |
PRKAA1 | Q13131 | protein kinase AMP-activated catalytic subunit alpha 1 | Kinase | 0.14 | 0.453 | 0.846 |
PRKAA2 | P54646 | protein kinase AMP-activated catalytic subunit alpha 2 | Kinase | 3.5E-08 | 0.456 | 0.846 |
PRKAB1 | Q9Y478 | protein kinase AMP-activated non-catalytic subunit beta 1 | Kinase | 5.3E-03 | 0.460 | 0.846 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
PVALB | P20472 | parvalbumin | Calcium-binding protein | 8.7E-02 | 0.547 | 0.692 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |