Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
TCF4 | P15884 | transcription factor 4 | Transcription factor | 1.00 | 0.464 | 0.846 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
HDAC9 | Q9UKV0 | histone deacetylase 9 | Epigenetic regulator | 1.00 | 0.439 | 0.846 |
ERBB4 | Q15303 | erb-b2 receptor tyrosine kinase 4 | Kinase | 1.00 | 0.455 | 0.846 |
MST1 | P26927 | macrophage stimulating 1 | Enzyme | 4.8E-19 | 0.465 | 0.885 |
HDAC1 | Q13547 | histone deacetylase 1 | Epigenetic regulator | 0.61 | 0.460 | 0.846 |
HDAC2 | Q92769 | histone deacetylase 2 | Epigenetic regulator | 1.00 | 0.476 | 0.846 |
MUL1 | Q969V5 | mitochondrial E3 ubiquitin protein ligase 1 | 1.9E-06 | 0.473 | 0.808 | |
CBLL2 | Q8N7E2 | Cbl proto-oncogene like 2 | Enzyme | 0.476 | 0.808 | |
HTR1A | P08908 | 5-hydroxytryptamine receptor 1A | G-protein coupled receptor | 0.20 | 0.522 | 0.846 |
CDKL5 | O76039 | cyclin dependent kinase like 5 | Kinase | 1.00 | 0.522 | 0.692 |
FOXG1 | P55316 | forkhead box G1 | 0.94 | 0.522 | 0.692 |