Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
HDAC9 Q9UKV0 histone deacetylase 9 Epigenetic regulator 1.00 0.439 0.846
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885
HDAC1 Q13547 histone deacetylase 1 Epigenetic regulator 0.61 0.460 0.846
HDAC2 Q92769 histone deacetylase 2 Epigenetic regulator 1.00 0.476 0.846
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692