Disease: Leigh Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
COQ8A Q8NI60 coenzyme Q8A Kinase 9.3E-11 0.674 0.385
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
COX3 P00414 cytochrome c oxidase III Enzyme 0.546 0.808
COX5A P20674 cytochrome c oxidase subunit 5A Enzyme 0.49 0.515 0.846
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
CPOX P36551 coproporphyrinogen oxidase Enzyme 0.17 0.488 0.846
CYTB P00156 cytochrome b 0.529 0.808
GFM2 Q969S9 G elongation factor mitochondrial 2 Enzyme 1.5E-18 0.736 0.269
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND3 P03897 NADH dehydrogenase, subunit 3 (complex I) 0.604 0.654
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
NDUFA1 O15239 NADH:ubiquinone oxidoreductase subunit A1 0.55 0.636 0.423
NDUFS1 P28331 NADH:ubiquinone oxidoreductase core subunit S1 Enzyme 6.6E-11 0.595 0.692
NDUFV1 P49821 NADH:ubiquinone oxidoreductase core subunit V1 6.4E-11 0.617 0.538
NPTX2 P47972 neuronal pentraxin 2 3.1E-02 0.617 0.615
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
RNR2 Q8IVG9 l-rRNA 0.603 0.692
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
TRMU O75648 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 1.5E-16 0.716 0.385