Disease: Marfan Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
DCN P07585 decorin 0.31 0.457 0.808
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
ELN P15502 elastin 2.1E-14 0.415 0.885
LOX P28300 lysyl oxidase 0.99 0.447 0.846
LTBP2 Q14767 latent transforming growth factor beta binding protein 2 Calcium-binding protein 7.4E-04 0.572 0.692
MMP12 P39900 matrix metallopeptidase 12 Enzyme 0.484 0.885
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PGR-AS1 PGR antisense RNA 1 0.514 0.808
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769