PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
AKT1 |
P31749
|
AKT serine/threonine kinase 1
|
Kinase
|
0.98 |
0.311 |
0.962 |
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
PIK3CD |
O00329
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
|
Kinase
|
1.00 |
0.319 |
0.885 |
PIK3CG |
P48736
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
|
Kinase
|
1.4E-06 |
0.320 |
0.885 |
PIK3CB |
P42338
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
|
Kinase
|
1.00 |
0.322 |
0.885 |
MAPK1 |
P28482
|
mitogen-activated protein kinase 1
|
Kinase
|
1.00 |
0.330 |
0.923 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
EGF |
P01133
|
epidermal growth factor
|
|
8.5E-17 |
0.357 |
0.923 |
PTPN11 |
Q06124
|
protein tyrosine phosphatase non-receptor type 11
|
|
1.00 |
0.385 |
0.923 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
EPHB2 |
P29323
|
EPH receptor B2
|
Kinase
|
1.00 |
0.374 |
0.846 |
MAPK3 |
P27361
|
mitogen-activated protein kinase 3
|
Kinase
|
3.7E-02 |
0.379 |
0.885 |
NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
FBN1 |
P35555
|
fibrillin 1
|
Calcium-binding protein
|
1.00 |
0.417 |
0.846 |
RAF1 |
P04049
|
Raf-1 proto-oncogene, serine/threonine kinase
|
Kinase
|
0.85 |
0.418 |
0.885 |
MAP2K7 |
O14733
|
mitogen-activated protein kinase kinase 7
|
Kinase
|
1.00 |
0.419 |
0.808 |
TSC1 |
Q92574
|
TSC complex subunit 1
|
|
1.00 |
0.440 |
0.808 |
MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
NF1 |
P21359
|
neurofibromin 1
|
Enzyme modulator
|
0.90 |
0.440 |
0.885 |
SOS1 |
Q07889
|
SOS Ras/Rac guanine nucleotide exchange factor 1
|
Enzyme modulator
|
1.00 |
0.485 |
0.808 |
SLC12A3 |
P55017
|
solute carrier family 12 member 3
|
Transporter
|
3.0E-32 |
0.493 |
0.808 |
RASA1 |
P20936
|
RAS p21 protein activator 1
|
Enzyme modulator
|
1.00 |
0.481 |
0.885 |