Disease: Common Variable Immunodeficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BLK P51451 BLK proto-oncogene, Src family tyrosine kinase Kinase 8.3E-14 0.585 0.769
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CD86 P42081 CD86 molecule 0.95 0.483 0.769
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
EBI3 Q14213 Epstein-Barr virus induced 3 Signaling 0.11 0.474 0.808
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731
IFNA1 P01562 interferon alpha 1 0.371 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808
IL21 Q9HBE4 interleukin 21 0.63 0.441 0.769
IL21R Q9HBE5 interleukin 21 receptor Receptor 1.00 0.550 0.731
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962