Disease: Cardiac fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
HDAC1 Q13547 histone deacetylase 1 Epigenetic regulator 0.61 0.460 0.846
HDAC9 Q9UKV0 histone deacetylase 9 Epigenetic regulator 1.00 0.439 0.846
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
F2RL1 P55085 F2R like trypsin receptor 1 G-protein coupled receptor 1.5E-04 0.480 0.769
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808