Disease: Cardiac fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IL6 P05231 interleukin 6 0.32 0.248 0.962
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
KLK1 P06870 kallikrein 1 Enzyme 1.5E-04 0.533 0.769
LOXL2 Q9Y4K0 lysyl oxidase like 2 3.4E-07 0.527 0.731
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MIR29C microRNA 29c 0.496 0.808
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
PGR-AS1 PGR antisense RNA 1 0.514 0.808
PLEKHA7 Q6IQ23 pleckstrin homology domain containing A7 6.2E-09 0.729 0.423
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
S100A4 P26447 S100 calcium binding protein A4 Calcium-binding protein 6.2E-03 0.448 0.769
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769