Disease: Hypothyroidism
Source: GWASCAT ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731
CD226 Q15762 CD226 molecule 3.9E-02 0.548 0.769
CD247 P20963 CD247 molecule 1.7E-02 0.539 0.731
DLEU1 O43261 deleted in lymphocytic leukemia 1 0.47 0.569 0.692
ELMO1 Q92556 engulfment and cell motility 1 Signaling 0.90 0.608 0.615
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
ITK Q08881 IL2 inducible T cell kinase Kinase 3.1E-08 0.555 0.769
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769
LINC00299 Q6ZSB3 long intergenic non-protein coding RNA 299 0.743 0.346
LINC02357 long intergenic non-protein coding RNA 2357 0.805 0.231
LPP Q93052 LIM domain containing preferred translocation partner in lipoma Enzyme modulator 7.2E-03 0.543 0.769
NEK6 Q9HC98 NIMA related kinase 6 Kinase 3.9E-02 0.743 0.385
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
PDE8B O95263 phosphodiesterase 8B 1.00 0.638 0.500
PIK3R5 Q8WYR1 phosphoinositide-3-kinase regulatory subunit 5 0.30 0.700 0.500
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
PVT1 Pvt1 oncogene 0.495 0.731
RAB5B P61020 RAB5B, member RAS oncogene family 2.6E-02 0.722 0.346
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769
TG P01266 thyroglobulin Enzyme modulator 2.9E-59 0.480 0.808