Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731
ANGPTL3 Q9Y5C1 angiopoietin like 3 Signaling 1.6E-13 0.584 0.577
APOA5 Q6Q788 apolipoprotein A5 5.6E-10 0.587 0.615
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APOH P02749 apolipoprotein H 1.6E-15 0.563 0.769
CARM1 Q86X55 coactivator associated arginine methyltransferase 1 Epigenetic regulator 1.00 0.601 0.692
CELSR2 Q9HCU4 cadherin EGF LAG seven-pass G-type receptor 2 G-protein coupled receptor 1.00 0.656 0.577
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
COL9A1 P20849 collagen type IX alpha 1 chain 3.1E-19 0.566 0.731
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
INSIG2 Q9Y5U4 insulin induced gene 2 6.0E-02 0.653 0.500
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LIPG Q9Y5X9 lipase G, endothelial type Enzyme 1.0E-10 0.633 0.615