Disease: Alzheimer Disease, Late Onset
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
ABCA4 P78363 ATP binding cassette subfamily A member 4 Transporter 5.3E-48 0.493 0.769
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BLOC1S3 Q6QNY0 biogenesis of lysosomal organelles complex 1 subunit 3 4.1E-03 0.729 0.385
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
ECE1 P42892 endothelin converting enzyme 1 Enzyme 0.96 0.541 0.769
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
GAB2 Q9UQC2 GRB2 associated binding protein 2 Receptor 0.98 0.563 0.692
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HLA-DRA P01903 major histocompatibility complex, class II, DR alpha Immune response 0.52 0.581 0.769
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808