Disease: Heart failure
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
CD40 P25942 CD40 molecule 0.85 0.396 0.846
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846