Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F7 P08709 coagulation factor VII Enzyme 1.3E-05 0.623 0.615
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IRF3 Q14653 interferon regulatory factor 3 Transcription factor 1.2E-04 0.517 0.808
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
KRIT1 O00522 KRIT1 ankyrin repeat containing 6.9E-04 0.500 0.808
LAD1 O00515 ladinin 1 Cellular structure 1.8E-14 0.584 0.731
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
LRP8 Q14114 LDL receptor related protein 8 1.00 0.644 0.346
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
MSRA Q9UJ68 methionine sulfoxide reductase A Enzyme 1.5E-15 0.608 0.615
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
NR1H3 Q13133 nuclear receptor subfamily 1 group H member 3 Nuclear receptor 0.90 0.566 0.692