Disease: Tumor Promotion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962