Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
ABL1 | P00519 | ABL proto-oncogene 1, non-receptor tyrosine kinase | Kinase | 1.00 | 0.432 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
CASP8 | Q14790 | caspase 8 | Enzyme | 3.7E-06 | 0.404 | 0.923 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
IFNA1 | P01562 | interferon alpha 1 | 0.371 | 0.923 | ||
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
SERPINA1 | P01009 | serpin family A member 1 | Enzyme modulator | 6.8E-08 | 0.410 | 0.923 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PLAU | P00749 | plasminogen activator, urokinase | Enzyme | 2.3E-06 | 0.425 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 |