Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TPM3 | P06753 | tropomyosin 3 | Cellular structure | 6.7E-03 | 0.490 | 0.808 |
STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
RASSF1 | Q9NS23 | Ras association domain family member 1 | Enzyme modulator | 4.9E-06 | 0.420 | 0.808 |
SERPINA1 | P01009 | serpin family A member 1 | Enzyme modulator | 6.8E-08 | 0.410 | 0.923 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |