Disease: Acoustic Neuroma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962