Disease: Endometrial Hyperplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
HOXA10 P31260 homeobox A10 0.88 0.538 0.692
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
NCOA3 Q9Y6Q9 nuclear receptor coactivator 3 Kinase 0.54 0.522 0.654
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962