Disease: Undifferentiated carcinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
IFNA1 P01562 interferon alpha 1 0.371 0.923
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885